Benzoic acid, 2-bromo-4-(bromomethyl)-, methyl ester

Benzoic acid, 2-bromo-4-(bromomethyl)-, methyl ester - Names and Identifiers

Name	Methyl-2-bromo-4-bromomethylbenzoate
Synonyms	Methyl 2-bromo-4-(bromomethyl) METHYL-2-BROMO-4-BROMOMETHYLBENZOATE Methyl-2-bromo-4-bromomethylbenzoate methyl 2-bromo-4-(bromomethyl)benzoate Benzoic acid, 2-bromo-4-(bromomethyl)-, methyl ester
CAS	128577-48-0
EINECS	1312995-182-4
InChI	InChI=1/C9H8Br2O2/c1-13-9(12)7-3-2-6(5-10)4-8(7)11/h2-4H,5H2,1H3

Benzoic acid, 2-bromo-4-(bromomethyl)-, methyl ester - Physico-chemical Properties

Molecular Formula	C9H8Br2O2
Molar Mass	307.97
Density	1.780±0.06 g/cm3(Predicted)
Melting Point	53 - 56°C
Boling Point	340.3±32.0 °C(Predicted)
Flash Point	159.581°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Soluble)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic, Moisture Sensitive
Refractive Index	1.59

Benzoic acid, 2-bromo-4-(bromomethyl)-, methyl ester - Introduction

Methyl ester 2-bromo-4-bromomethylbenzoic acid, chemical formula C9H7Br2O2, is an organic compound.

Nature:
-Appearance: White solid powder.
-Solubility: Soluble in organic solvents, such as alcohol, ether, etc.
-Melting point: about 180-181 degrees Celsius.

Use:
Methyl 2-bromo-4-bromomethylbenzoic acid is commonly used in organic synthesis, mainly in the fields of medicine, dyes and pesticides.
For example, it can be used as a catalyst and intermediate for pesticides, and used as a raw material for the synthesis of anti-tumor drugs in the pharmaceutical industry.

Preparation Method:
Methyl ester 2-bromo-4-bromomethylbenzoic acid can be prepared by the following steps:
1. 2-bromo-4-bromomethylbenzoic acid is reacted with anhydride to generate the corresponding anhydride ester.
2. The anhydride ester is reacted with alcohol and base to generate methyl ester 2-bromo-4-bromomethylbenzoic acid.

Safety Information:
Methyl ester 2-bromo-4-bromomethylbenzoic acid has low safety and may have certain pathogenicity and irritation. During use, it is necessary to wear appropriate protective measures, such as gloves, protective glasses and laboratory coats. At the same time, to avoid prolonged contact with the skin and inhalation of its dust. In case of accidental contact or inhalation, rinse immediately with plenty of water. If necessary, seek medical attention immediately.

Last Update：2024-04-09 21:11:58